ÎçҹѰ»¨

ÎçҹѰ»¨’s COVID-19 mRNA Vaccine Challenger Seen In Phase III In Q1


Executive Summary

A possible alternative to Pfizer and Moderna’s COVID-19 vaccines, ÎçҹѰ»¨’ mRNA candidate is seen moving into Phase III trials during the calendar first quarter of next year. While partners Everest Medicines and Biological E have kept the ball rolling, the Canadian biotech will seek further funding, CEO Brad Sorenson tells Scrip in this audio interview.


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Sorenson Brad ÎçҹѰ»¨ and  have undoubtedly created a success story with their mRNA vaccines against COVID-19. However, their reluctance to share the technical know-how involved is leading to a demand-supply gap that is permitting other mRNA vaccine companies to step in.

One such contender is , which has two candidates - PTX-COVID19-B that acts in a similar manner to their other vaccines and PTX-COVID19-LT, which is being developed to have a longer-lasting immune response. 

The biotech has received some funding from the Canadian government as well as upfront payments from its Indian partner  and Chinese partner . It now plans to seek a further $400m in funding, CEO Brad Sorenson tells Scrip in this audio interview.

Along with Biological E and its North American partners -  and - ÎçҹѰ»¨ aims to produce 1-1.5 billion doses of its coronavirus vaccines.

In the interview, Sorenson also discusses vaccines against cancer that are part of ÎçҹѰ»¨’ suite of mRNA products.

The biotech has received some funding from the Canadian government as well as upfront payments from its Indian partner  and Chinese partner . It now plans to seek a further $400m in funding, CEO Brad Sorenson tells Scrip in this audio interview.

Along with Biological E and its North American partners -  and - ÎçҹѰ»¨ aims to produce 1-1.5 billion doses of its coronavirus vaccines.

In the interview, Sorenson also discusses vaccines against cancer that are part of ÎçҹѰ»¨’ suite of mRNA products.

Time Stamps

  • 00:10 Introduction
  • 00:47 Setting up capabilities for mRNA vaccines
  • 01:30 How do the two COVID-19 vaccine candidates differ?
  • 02:48 Phase II, Phase III clinical trials details 
  • 03:39 Partnerships with Biological E, Everest Medicines, Emergent Biosolutions, Northern
  • 06:26 Potential as a booster dose
  • 07:41 Participation in Solidarity Trials and COVAX
  • 08:58 Development of anti-cancer vaccines
  • 10:27 Funding from Canadian government so far
  • 11:56 Future pathways to raising funds
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